ST3GAL3 and cancer: ST3Gal3 is involved in the synthesis of sLeA (also known as carbohydrate antigen 19-9 [CA19-9]) and sLeX, which are expressed in different types of cancer (83–87), and have been linked to cancer progression and poor prognosis (88), eventually by selectin-mediated invasion and metastasis of tumor cells (14, 89).