LGI1 and encephalitis: Currently, AE is responsible for 20% of all types of encephalitis (8), of which anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis is the most common, accounting for approximately 80% of AEs, followed by leucine-rich glioma inactivated 1(LGl1) antibody, anti-gamma-aminobutyric acid-B receptor (GABABR) antibody, anti-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) antibody, and anti-dipeptidyl-peptidase-like protein 6 (DPPX) antibody encephalitis (9–12).