Indeed, analysis of the MoMac-VERSE in cancers shows that IL4I1 macrophages, a population of macrophages that co-express IDO1 and PD-L1, preferentially express TGF-b and CD48 as compared to C1Q+ and TREM+ macrophages which preferentially express MARCO and MS4A4a, respectively [Figure 2 (38)]. This evidence concerns the gene CD274 and cancer.