LGALS7B and psoriasis: Other reports however, indicate that gal-7 has anti-inflammatory actions treatment of PMA-stimulated Jurkat cells with gal-7 inhibits IL-2 and INF-γ production (112), gal-7 silencing elevates IL-17A-stimulated HaCaT cell secretion of IL-6 and IL-18 (107) and gal-7 is down-regulated in a mouse model of psoriasis (107).