Immunostainings of consecutive (3 μm serial) CRC tissue sections, from short-term survivors of the validation cohort, revealed a distinct expression of TIGIT, IDO1 and PD-L2 among the neoplastic glands, mostly in the areas infiltrated by EOMES+T-bet+NKp46+ cells. The gene discussed is PDCD1LG2; the disease is colorectal carcinoma.