BSG and rheumatoid arthritis: We note that TCZ decreased miR-146a-5p levels and increased EMMPRIN levels in fibroblasts in vitro (Figures 7E, G, 8C, D, 9N, O), whereas it increased miR-146a-5p levels and decreased EMMPRIN levels in the serum samples from treated RA patients (Figures 1, 3).