The analysis showed the significant genes expressed in other studies are CXCL1, CXCL6, CXCL8, IL33, TIMP1, IL18, IFNGR2, TRIM27, TRIM28, IFI6, XAF1, CXCL5, IFIT1, IL6, IL10, and CSF2, etc. The analysis will help to understand the DEGs in mild and severe COVID-19 patients. Here, XAF1 is linked to COVID-19.