The analysis showed the significant genes expressed in other studies are CXCL1, CXCL6, CXCL8, IL33, TIMP1, IL18, IFNGR2, TRIM27, TRIM28, IFI6, XAF1, CXCL5, IFIT1, IL6, IL10, and CSF2, etc. The analysis will help to understand the DEGs in mild and severe COVID-19 patients. The gene discussed is TIMP1; the disease is COVID-19.