Cerebrospinal fluid-Protein (C-Pro), Cerebrospinal fluid-Albumin (C-ALB), C-IgG, QALB and QIgG were higher in the GBS and CIDP groups than in the control group, while Cerebrospinal fluid-white blood cell (C-WBC) (P < 0.05), S-ALB and the IgG index (P < 0.01) in the GBS and CIDP groups were lower than those in the control group. The gene discussed is ALB; the disease is Guillain-Barre syndrome.