In a previous study, a sub-toxic dose of myricetin incubation (50 μM) has been shown to enhance tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis of glioblastoma cells by augmenting the activation of caspases-3/-7/-8/-9 (Siegelin et al., 2009). This evidence concerns the gene TNFSF10 and glioblastoma.