CASP3 and lung cancer: A study on the lung cancer cell lines A549 and 95D conducted by Huang et al. (2018) showed that TMP decreased cell viability in a dose- and time-dependent manner and suppressed the carcinogenesis of lung cancer cells by arresting the cell cycle at the S phase and inducing mitochondria-dependent apoptosis by regulating caspase-3 and Bax/Bcl-2.