TARDBP and amyotrophic lateral sclerosis: The dysregulation of GluA1 also appears conserved amongst other genetic ALS backgrounds including mutant TDP-43 motor neurons (Bursch et al., 2019), FUS (Udagawa et al., 2015) and in sporadic ALS patients, where the latter show further dysregulation of AMPA receptor subunits in the cortex (Gregory et al., 2020).