RBP gene mutations including TDP-43, FUS, Ataxin-2 (ATXN2), RBP EWS (EWSR1), TATA-box binding protein-associated factor 15 (TAF15), heterogeneous nuclear ribonucleoprotein A1 (hnRNPA1), heterogeneous nuclear ribonucleoprotein A2/B1 (hnRNPA2/B1), TIA1 cytotoxic granule associated RNA binding protein (TIA1), and matrin3 (MATR3) are reported in FALS and FTD cases, which comprises ~10% and 50% of the total cases, respectively (Kabashi et al., 2008; Elden et al., 2010; Ticozzi et al., 2011; Couthouis et al., 2012; Kim et al., 2013; Johnson et al., 2014; Mackenzie et al., 2017). Here, HNRNPA1 is linked to frontotemporal dementia.