An electron microscopy study showed the disappearance of microvilli in the sural nerve biopsy specimen from an anti-NF186 IgG3 antibody patient with CIDP, which were replaced by elongated extensions of Schwann cell cytoplasm, so that the nodal gap was occluded (Vallat et al., 2018). This evidence concerns the gene IGHG3 and chronic inflammatory demyelinating polyradiculoneuropathy.