In the recent years, antibodies to neurofascin 155 (NF155), contactin 1 (CNTN1), contactin-associated protein 1 (CASPR1), and neurofascin 186 (NF186) have been implicated in the pathogenesis of CIDP via functional impairment of the node of Ranvier. The gene discussed is CNTN1; the disease is chronic inflammatory demyelinating polyradiculoneuropathy.