In a previous study (Zhang et al., 2018), increased levels of FAM19A5 in oligodendrocyte precursor cells of traumatic brain injury-induced FAM19A5-LacZ KI mouse penumbra, which supported a positive role of neuroinflammation in the repair process during the early stages of PD (Shahapal et al., 2019). This evidence concerns the gene TAFA5 and brain injury.