Since CRYAB has been identified as a scaffold to complex with other proteins for signal transduction 55, 56 and the PPIs between LBH and CRYAB in NPC cells were confirmed in our previous research 10, we tested the potential PPIs between CRYAB and VEGFA, as well as between LBH and VEGFA in HUVECs. This evidence concerns the gene CRYAB and nasopharyngeal carcinoma.