VEGFA and nasopharyngeal carcinoma: Moreover, VEGFA downregulation led to less extracellular VEGFA secretion from both NPC cells and HUVECs treated with LBH+ exosomes, resulting in decreased VEGFA levels in the interstitium of NPC tissues and weakened phosphorylation of VEGFR, which is in accordance with the mitigated EMT progression and angiogenesis we observed.