In NPC cells treated with LBH+ exosomes, LBH upregulation was observed to synchronize with mitigated EMT progression, as well as the inhibition of CRYAB expression and phosphorylation, which is consistent with our previous results in stable LBH-overexpressing NPC cell lines 10; additionally, VEGFA expression declined upon this exosome-induced LBH upregulation. The gene discussed is LBH; the disease is nasopharyngeal carcinoma.