EEA1 and nasopharyngeal carcinoma: In our study, the LBH protein colocalized with the vesicle marker EEA1 in NPC cells, which is consistent with its subcellular localization in vesicles (GO:0043231) approved by the Human Protein Atlas 43, implying its possible secretion via exosomes; additionally, elevated LBH at both the mRNA and protein levels was detected in exosomes derived from LBH-overexpressing NPC cells.