There were 19 of the 123 genes that were deleted in more than 5% of the human PPAPA/TP53I breast cancers, including POLR3A (8.6%), SH2D4B (7.9%), ANXA11 (7.5%), SFTPD (7.5%), TSPAN14 (7.2%), ADK (6.6%), and DYDC2 (6.5%) (Table 1, and Supplementary Table S5). This evidence concerns the gene POLR3A and breast cancer.