DNASE1L3 and hepatocellular carcinoma: To explore the functional effects of DNASE1L3 in different HCC subtypes, we chose Huh7 and HCCLM3 cells as DNASE1L3 overexpression models, while HepG2 cell was chosen as the knock-down model based on DNASE1L3 expression level in 5 HCC cell lines for subsequent experiments.