On the other hand, belimumab, a BAFF antibody, has been used in SLE patients with B cell occurring seropositivity 97, 101 and clinical trials have been conducted with tabalumab/ LY2127399 antibody for RRMS, although no indication of treatment effect was confirmed 97, 98. The gene discussed is TNFSF13B; the disease is systemic lupus erythematosus.