As illustrated in Figure 10, compared to the control group, the relative mRNA levels of Traf1 and Raet1e were significantly increased compared to the control group (P < 0.05) and the AD group showed significantly decreased mRNA levels of Wnt7b, Gpr174, Ptbp3, Mrpl23 and Armcx5. Among them, the differential expression trends of Wnt7b, Gpr174, Ptbp3, Mrpl23, Armcx5 and Raet1e are consistent with the trends in GSE44770 dataset. This evidence concerns the gene GPR174 and Alzheimer disease.