In addition, studies that integrate schizophrenia GWAS data with eQTL/splicing quantitative trait loci operating in the human fetal brain provide evidence for altered prenatal regulation of several genes involved in neurite outgrowth in association with genetic risk for the condition, including CNTN4 (39,52) and genes within the protocadherin alpha cluster (55,56). This evidence concerns the gene CNTN4 and schizophrenia.