MYO1E and neoplasm: Myo1e is involved in receptor mediated endocytosis [99,100] and recently was described as an essential component in invadosomes [101], these structures are important to degrade extracellular matrix and promote cell migration and invasion, the same group reported that Myo1e promotes tumor progression and metastasis in breast cancer by induction of proliferation and tumor cell de-differentiation [28].