However, their possible role in cystic kidney formation can be hypothesized because KMT2D protein is known to be expressed in the metanephros of mice (http://www.informatics.jax.org/) as well as in the human kidney (https://www.proteinatlas.org/ENSG00000167548-KMT2D/tissue). This evidence concerns the gene KMT2D and urogenital neoplasm.