Although the survival benefit with regard to THEMIS2 for breast cancer patients who received chemotherapy diminished in the updated data base in the KM Plotter analysis, we did find that overexpression of THEMIS2 correlated with poor prognosis in TNBC patients by Oncolink database (https://www.oncolink.org/cancers/breast, Fig. 7C) and Oncomine database (https://www.oncomine.org/resource/login.html, Fig. 7D). This evidence concerns the gene THEMIS2 and breast carcinoma.