They occurred in 77 individuals and included variants reported in familial Mediterranean fever (MEFV), familial cold inflammatory syndrome type 2 (NLRP12), TNF receptor-associated periodic syndrome (TNFRSF1A), Blau syndrome (NOD2), pyogenic sterile arthritis, pyoderma gangrenosum acne syndrome (PSTPIP1), and CARD14-mediated pustular psoriasis (CARD14). The gene discussed is PSTPIP1; the disease is familial Mediterranean fever.