TNF and neoplasm: Recently, in the study of subcutaneous tumor model of mouse melanoma, it was found that cell-penetrating peptide (CPP) and TNF-α-Anchored exosomes and superparamagnetic iron oxide nanoparticles (CTNF-α-exosome-SPION) coupling enhanced tumor targeting of TNF-α-exosomes under the action of external MFs.