When analysis was repeated in the depression cohort only, no correlation was detected between the CP volume and [11C]PK11195 DVR in any of the main ROIs (ACC: r = 0.20, p = 0.40; PFC: r = 0.18, p = 0.18; INS: r = 0.17, p = 0.2). Here, CP is linked to depressive symptom measurement.