CD274 and neoplasm: Conversely, E7 RNA-LPX vaccination strongly increased the expression of MHC class I molecules, PD-L1 and, to a lesser extent, Qa-1b (Fig. 3c) on tumor cells, despite not changing the total tumor cell count (Fig. 3a) and only slightly increasing CC3 and Fas expression on tumor cells (Fig. 3b, c) when compared to control RNA-LPX.