D'Arcangelo et al. assessed melanoma using a multi‐omics approach (D'Arcangelo et al., 2016); based on transcriptomics and miRNAomics, the authors were able to find several clues on the pathways affected by PDGFRα, a known inhibitor of angiogenesis and melanoma proliferation. The gene discussed is PDGFRA; the disease is melanoma.