However, no studies have shown that ferroptosis is involved in the development of dilated cardiomyopathy; Moreover, pyroptosis is also another form of cell death, which has only been shown in one study that NLRP3 inflammasome-mediated pyroptosis contributes to the pathogenesis of non-ischemic dilated cardiomyopathy (33). The gene discussed is NLRP3; the disease is dilated cardiomyopathy.