CD14 and bacterial infectious disease: Similar studies have also reported LRR as the important domain against bacterial infections in case of CD14 molecule in cattle (Stetson and Medzhitov, 2006), goat (Vercammen et al., 2008a; Schlee et al., 2009), and buffalo (Pal and Chatterjee, 2009; Pal et al., 2013).