The symptoms of suspicious bone lesions in patients with a history of GC or bone lesions and suspicious bone lesions and gastric lesions simultaneously by 18F-FDG PET/CT could alert physicians to monitor clinical indicators, including ALP, LDH, CEA and CA19-9 levels, for the diagnosis of BM and thus for the development of a precise treatment plan. Here, CEACAM5 is linked to gastric cancer.