PFKFB4 and hepatocellular carcinoma: In line with this notion, we found that LINC01572 knockdown significantly inhibited the glycolytic process, which was effectively reversed by PFKFB4 overexpression (Figures 7A,C,E), whereas LINC01572 overexpression promoted HCC glycolysis, and PFKFB4 silencing remarkably blunted this effect (Figures 7B,D,F,H).