Considering the significance of glycolysis in HCC malignancy (Hu L. et al., 2019; Feng et al., 2020; Gu et al., 2020), we reckoned that LINC01572 might have a glycolysis-promoting potential via increase in the PFKFB4 level. This evidence concerns the gene PFKFB4 and hepatocellular carcinoma.