PFKFB4 and hepatocellular carcinoma: Subsequently, using high-throughput screening and various confirmatory experiments, we presented evidence showing that 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 4 (PFKFB4) is a critical target molecule to mediate LINC01572/miR-195-5p effects in HCC.