POM121 and colorectal cancer: POM121 has also been linked as a potential prognostic biomarker in oral squamous cell carcinoma (OSCC) (64), colorectal cancer (CRC) (65), laryngeal cancer (LRC) (66), and non-small-cell lung cancer (NSCLC) (63), where elevated levels of POM121 are linked to advanced tumor-node-metastasis (TNM) stages.