For KEGG analysis, the most significant pathways are all associated with oxidative stress, namely, pathways in cancer [29], lipid and atherosclerosis [30], and fluid shear stress and atherosclerosis [31]; AGE-RAGE pathway [32]; TNF pathway [33]; IL-17 pathway [34]; and microbial infection-related pathways [35]. The gene discussed is RENBP; the disease is cancer.