Nine pathways were only significantly enriched in the liver (Metabolism of xenobiotics by cytochrome P450, Monobactam biosynthesis, Inositol phosphate metabolism, Glycerophospholipid metabolism, Cellular senescence, p53 signaling pathway, Mismatch repair, Central carbon metabolism in cancer, and RIG-I-like receptor signaling pathway). This evidence concerns the gene TP53 and cancer.