Although no statistical differences were in the allelic and genotype frequencies comparisons, probably due to the small sample size, differences in the genotype frequency distributions of IL-10 (rs1800871 and rs1800872) and CD209 (rs2287886 and rs4804803) SNPs were observed between schistosomiasis patients with fibrosis and without fibrosis. This evidence concerns the gene CD209 and schistosomiasis.