NK cells transduced with a viral vector encoding CXCR2 demonstrated better motility to renal cell carcinoma tumors expressing cognate ligands such CXCL1, CXCL2, CXCL5, CXCL6 and CXCL8 (170). The gene discussed is CXCL2; the disease is hereditary clear cell renal cell carcinoma.