TFEB and Cognitive impairment: In the co-dominant model, subjects carrying the TFEB rs14063AG genotype had an increased risk of cognitive impairment relative to those with the GG genotype, and the risk of cognitive impairment was 1.553 times higher in the AG carriers than in the GG carriers (co-dominant model: adjusted OR = 1.553, Bonferroni correction confidence interval = 1.007–2.397, P = 0.007).