Detection of fluid biomarkers of amyloid plaque and tau protein has been applied in stroke patients, and their levels would vary according to sampling time point, vascular lesion characteristics, and coexisting neurodegeneration states (Hesse et al., 2000; Zhang et al., 2010; Bielewicz et al., 2011; Skillback et al., 2015). The gene discussed is MAPT; the disease is stroke disorder.