MAPT and ischemic stroke: In this study, we aimed to explore: (1) the associations of plasma Aβ40, Aβ42, and tau protein levels with cognitive presentations around 3 months after first-ever ischemic stroke; and (2) the relationships of plasma Aβ40, Aβ42, and tau protein with the relevant imaging markers, such as cortical atrophy on MRI and amyloid burden on PET imaging.