SACS and cerebellar ataxia: Since abnormal zebrin expression has been observed in rodent models of other forms of ataxia (Sawada et al., 2009; Sarna and Hawkes, 2011; Bailey et al., 2014; White et al., 2021), the changes in anterior-lobule firing that we previously reported (Ady et al., 2018) may likewise arise from abnormal expression of zebrin in the cerebellum in Sacs–/– mice.