Recently, studies showed that the pro-inflammatory and multifunctional IL-6 cytokine was increased in both ALS and FTD patients in comparison to controls (Galimberti et al., 2015; Gibbons et al., 2015; Ngo et al., 2015; Lu et al., 2016; Tortelli et al., 2020). This evidence concerns the gene IL6 and frontotemporal dementia.