While mutations in the progranulin gene (GRN) and the microtubule-associated protein tau (MAPT) have been identified as major causes of familial FTD (Greaves and Rohrer, 2019), some other genes were linked only to ALS, including kinesin family member 5A (KIF5A) and SOD1 (superoxide dismutase 1). This evidence concerns the gene GRN and amyotrophic lateral sclerosis.