Park et al. examined in 2012 by methylation specific PCR promoter hypermethylation of a six gene panel (NPTX2, UCHL1, SARP2, ppENK, p16 and RASSF1A) in plasma cell-free DNA of PDAC patients (n = 16), patients with chronic pancreatitis (n = 13), and healthy individuals (n = 29). The gene discussed is NPTX2; the disease is chronic pancreatitis.