TNFRSF1A and neoplasm: Moreover, a recent study reports the overexpression of the mesenchymal-associated TNFRSF1A to be strongly related to poor prognosis, and its knockdown to inhibit proliferation and migration of tumor cell lines in vitro [45]; also, it seems to induce the production of IL-17 by CD4+ T cells, recruiting myeloid cells and supporting tumor growth [46].