Six of the studied genes have been associated with cancer, two with cardiac disease (LRRC2 and LRRC14B), one with Emery–Dreifuss muscular dystrophy (TMEM38A), one with myotonic dystrophy type 1 (ASB2), one with glaucoma (ASB10), one with Treacher Collins syndrome (a craniofacial disease; OSBPL11), and one with osteogenesis imperfecta (TMEM38B; Table S6). This evidence concerns the gene TMEM38A and Treacher-Collins syndrome.