Compared with the control group, some genes known to promote the development of endometriosis were decreased in the si-hsa_circ_0063526 agomir group, including MAPK-14, K-ras, N-cadherin, Vimentin, ER-α, ER-β (P < 0.05, Figure 12). The gene discussed is ESR2; the disease is endometriosis.