ABI1 and cancer: Notably, the role of ABI1 in cancer is not always the same; in some cancers, such as PMF, glioblastoma, and prostate cancer, ABI1 expression is downregulated [26, 27, 30, 31], whereas in breast cancer, ABI1 expression is enhanced [32], thus suggesting the tissue and disease‐involving pathway specificity of the role of ABI1 in oncogenic transformation and indicating the importance of mechanistic studies.