Thy-1 is silenced in lesional fibroblasts in IPF (Idiopathic Pulmonary Fibrosis), and its expression in murine lung fibroblasts is decreased with progression of experimental bleomycin induced lung fibrosis (Hagood et al., 2005; Sueblinvong et al., 2012). The gene discussed is THY1; the disease is pulmonary fibrosis.