Another study also demonstrated that the alkaline-extracted C. militaris polysaccharide CM3II (∼19.1 kDa), which consisted of →4)-β-D-Manp(1→6)-α-D-Manp(1→6)-β-D-Manp(1→ glycosyls, can attenuate atherosclerosis in apoE(-/-) mice (Yang et al., 2021). The gene discussed is APOE; the disease is atherosclerosis.