Mù xiāng ameliorated stomachache, diarrhea and hematochezia of rats. Body weight was increased. IL-1β, TNF-α, caspase-3, BAD were decreased. IL-6, IL-10, p53 and Bcl-2 were upregulated. The activity level of PI3K and Akt was increased. The gene discussed is IL1B; the disease is Hematochezia.