These genes include B3GALT6, B3GAT3, CSGALNACT2, CHPF, DSE, CHST11, CHST12, CHST13, CHST3, CHST7, UST, and CHST14, indicating that chondroitin sulfate biosynthesis enzymes play key roles in colorectal cancer (Figure 4). This evidence concerns the gene DSE and colorectal cancer.