Further analysis indicated that XYLT1, XYLT2, B4GALT7, B3GALT6, B3GAT3, CSGALNACT2, CHSY3, CHSY1, CHPF, CHST13, CHST7, CHST15, UST, and CHST14 were up/down-regulated in all clinical stages of COAD (Supplementary Figure S1). Here, XYLT2 is linked to colon adenocarcinoma.